BioMinF orthodontic toothpaste


 BioMin F : A breakthrough innovation that could significantly reduce dental decay.

Professor Hill

Braces and other orthodontic appliances can make cleaning of teeth difficult, the most common side effects include irritation of the gums and mouth and in 50% of cases white spot lesions.  A high remineralisation toothpaste can assist.

White Spots / Decalcification / Demineralisation

White spots (decalcification / demineralisation) are a common side effect that can occur in 50% of traditional orthodontic patients1. These spot white lesions can develop in as little as 4 weeks2, and are considered to be the first steps towards decay and cavitation3. Researchers have found white spots can form within the first month of fixed orthodontic appliance being used4.

White spots can be caused/exacerbated by many factors, three of which are fluorosis, hypocalcification, (lack of calcium) and orthodontics. Fluorosis can occur in from excessive intake of fluoride before all teeth are formed. White spots can also be caused by mineral loss in the tooth, a term called hypocalcification, with the white spots themselves called hypoplasia. White spots can also occur from poor dental health exacerbated by braces.

Whilst the demineralised tooths surface remains intact, there is a possibility of remineralisation and reversal of the lesion

Brown spots – can be caused by a number of issues and can be a sign of tooth decay. Brown spots can be plaque on the tooth’s surface which can turn into tartar, and can also be caused by having too much fluoride (fluorosis, especially in children).

BioMinF may assist with white spots in two ways: its slow release fluoride can assist in stopping decay (caries) whilst its high remineralisation rate may remineralise (replace) the lost calcium causing the white spots and strengthen the tooth and make it more acid resistant.

How to Prevent White spots

The best way to prevent white spots from occurring is from perfect brushing and flossing.

  • Drink water instead of soft drinks
  • Brush twice per day.
  • Use a low fluoride toothpaste
  • Floss nightly
  • Visit your dentist every 6 months.


Orthodontics patients can work on their diet to reduce the chances of decay. However, in many cases, their appliance (braces) makes it nearly impossible for good dental hygiene.  A protective orthodontic toothpaste such as BioMinF may be able to assist.

BioMin F shown to have a high capacity to remineralise / repair white spot lesions.

Compared to regular fluoride toothpaste, researchers have shown that BioMin F has a “high capacity” to remineralise white spot lesions associated with orthodontic appliances (braces)*. Results showed that BioMin F had a deep penetration of calcium and phosphate ions.  The unique slow release fluoride used in BioMin F helps drive the remineralisation process, this is aided by the availability of calcium and phosphate** on the tooths surface.


* Alghamdi., S et al, “BioMin can Remineralize White Spot Lesions Surrounding Orthodontic Brackets“. Presented at IADR San Francisco 2017

** Delia S., et al, “Fluoride-containing bioactive glasses: Effect of glass design and structure on degradation, pH and apatite formation in simulated body fluid” Acta Biomaterialia 6 (2010) 3275–3282

Slow-release fluoride a breakthrough in protective performance.

BioMinF’s patented technology turns the tables on traditional toothpaste.  Normally when you wash your teeth the level of available fluoride decreases quite rapidly 2 due to rinsing,  salivary secretion, and swallowing.  BioMinF’s patented technology significantly increases the level of therapeutically available fluoride for up to 12 hours after brushing.  (BioMinF actually uses up to 60% less fluoride than regular toothpaste.)

The availability of fluoride, calcium and phosphate helps stop decay and creates an armour on the tooth’s enamel surface.  The armour helps protect the tooth against decay and demineralisation/decalcification (caries) and the formation of white spot lesions.  When the tooth comes under attack from acids and sugars BioMinF responds by releasing additional essential minerals.

The constant supply of low levels of fluoride in biofilm / saliva / dental interface is considered beneficial in preventing dental decay. 

For fluoride to be beneficial for longer than the time of brushing, fluoride needs to be deposited and slowly released. Professor Ten Cate

How does fluoride prevent tooth decay
  1. Fluoride promotes remineralisation – tooth rebuilding and repair.
  2. Fluoride hardens the tooth and forms fluorapatite.

BioMinF actively remineralises teeth

BioMinF shows a higher remineralisation rate

BioMinF shows a higher remineralisation rate than many retail remineralising kinds of toothpaste and orthodontic mousses. Scientists believe that the slow release of fluoride, calcium and phosphate of BioMinF is the reason for the high remineralisation rate.

 BioMinF retards demineralisation with active acid resistance

Acids in the mouth cause demineralisation, decay and cavities. BioMinF actively works to neutralise acids by increasing its release of essential minerals. This helps to stop and reverse demineralisation process whilst strengthening the tooth and making it more acid resistant for the future.

Data on file : Queen Mary University London

Biomin family lge1

Less than 1/2 the fluoride of regular toothpaste

Lower fluoride content reduces the risk of fluorosis

BioMinF’s slow release mechanism uses fluoride more efficiently than regular toothpaste. BioMinF contains less than 600 ppm fluoride which is 40% lower than most ages 6+ toothpaste and more than 50% lower than regular adult toothpaste.

* BioMinF Armour for Teeth® available fluoride content when packed 600 ppm. Standard adult toothpaste is generally 1400 to 1500 ppm. Standard children aged 6+ toothpaste is generally 1,000 ppm fluoride.

References for: White Spots / Decalcification / Demineralisation

  1. Talic, Nabeel F. “Adverse Effects of Orthodontic Treatment: A Clinical Perspective.” The Saudi Dental Journal 23.2 (2011): 55–59.
  2. Ogaard B., Rolla J., Arends J. Orthodontic appliances and enamel demineralization. Part 1. Lesion development. Am. J. Orthod. Dentofacial Orthop. 1988;94:68–73
  3. Gorelick L., Geiger A., Gwinnett A. Incidence of white spot formation after bonding and banding. Am. J. Orthod. 1982;81:93–98
  4. Öggard B, Rølla G, Arends J. Orthodontic appliances and enamel demineralisation. Part 1. Lesion development. Am J Orthod Dento Orthop 1988; 94: 68–73.
  5. Geiger AM, Gorelick L, Gwinnett AJ, Griswold PG. The effect of a fluoride program on white spot formation during orthodontic treatment. Am J Orthod Dento Orthop1988; 93: 29–37

References :

  1. ten Cate J M, Featherstone J D. Mechanistic aspects of the interactions between fluoride and dental enamel. Crit Rev Oral Biol Med 1991; 2: 283–296.
  2. ten Cate J M,  Contemporary perspective on the use of fluoride products in caries prevention.  British Dental Journal 214, 161 – 167 (2013)
  3. ten Cate J M, Contemporary perspective on the use of fluoride products in caries prevention.  British Dental Journal 214, 161 – 167 (2013)