Clinical remineralisation comparison:  BioMin F vs 1450 ppm fluoride toothpaste.

BioMin F in comparison to standard 1450 ppm fluoride toothpaste, delivers a greater surface micro hardness, a smoother enamel surface and greater enamel volume restoration (remineralisation) 1.

Decay (also known as caries) is the most prevalent disease in the world affecting between 60% and 90% of the world’s population1. Decay is highly preventable through diet, fluoride usage and improved oral hygiene.

Demineralisation is the loss of minerals from the protective enamel layer of the tooth. It leads to a softening of the enamel surface and is the beginning of the decay process. The enamel also gets rougher and ultimately loses mass.

A clinical study by Farooq (University of Toronto, Canada) showed that BioMin is an effective remineralising agent that showed a significantly higher level of remineralising performance than regular fluoride toothpaste.

BioMin was shown to harden the tooths enamel and reduce the roughness by filling in the troughs or valleys formed by demineralisation. (This reduces plaque accumulation). BioMin was also able to increase the volume of the enamel by depositing fluorapatite to replenish the tooth structure for added protection. Farooq’s findings echo the results found by Omron in her study from July 21

MicrohardnessSurface RoughnessVolume Gain
(Micro CT Analysis)
Toothpaste1450 ppm fluoride BioMin F1450 ppm fluorideBioMin F1450 ppm fluoride BioMin F
Post Demineralisation211.28167.711114.199214.5416.82
Post brushing simulation (remineralisation)272.13285.521058.5768.814.5517.01
Gain % Loss23%35%7%29%6%45%

The slow release of calcium and phosphate as well as fluoride in BioMin F enhances the rate of remineralisation compared to a standard fluoride toothpaste. Remineralisation is central to the principles of preventive dentistry and BioMin F is shown here to be more effective at replacing lost mineral caused by acidic attack.

Standard fluoride toothpaste scavenges calcium and phosphate from saliva, but with BioMin these are delivered together in an optimised ratio to form stable, more acid resistant fluorapatite.

The continuous release of these ions at low concentration over several hours, rather than a high initial release also enhances the remineralisation process. BioMin contains approx. 65% less fluoride than the standard 1450 ppm fluoride comparator. This low concentration assists in the prevention of undesirable fluorite formation and also ensures the long-term delivery of fluoride ions for the formation of a stable fluorapatite layer, which is seen as the desired outcome. A lower level of fluoride should also reduce the risk associated with fluorapatite.

Demineralisation is the foundation of decay /caries, and a toothpaste that acts effectively to replenish tooth mineral could play a huge part in combating the disease. In addition, in the presence of acid in the mouth, (e.g consuming a fizzy drink) BioMin F’s smart technology enables it to start working quickly to reverse the early stages of demineralisation and to help neutralise the acidity.